| Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma |
Shaw, William Ph.D |
2013 |
Mental Disorders |
| Cholesterol Deficiency: A Major Factor in Many Chronic Disorders |
Shaw, William Ph.D |
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Mental Disorders |
| Lithium Deficiency: Common in Mental Illness and Social Ills |
Shaw, William Ph.D |
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Mental Disorders |
| Porphyrin Testing and Heavy Metal Toxicity: Unresolved Questions and Concerns |
Shaw, William Ph.D |
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Mental Disorders |
| Oxalates Control is a Major New Factor in Autism Therapy |
Shaw, William Ph.D |
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Mental Disorders |
| Candida and Overgrowth - The Problem & Bacteria By-products |
Shaw, William Ph.D |
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Mood Disorders |
| Associations between Acetaminophen Use during Pregnancy and ADHD Symptoms Measured at Ages 7 and 11 Years |
John M. D. Thompson, Karen E. Waldie mail, Clare R. Wall, Rinky Murphy, Edwin A. Mitchell, the ABC study group |
2014 |
Mental Disorders |
| Don't Suffer with OCD |
Rebecca Shannonhouse |
2013 |
Mental Disorders |
| Gut feelings: the future of psychiatry may be inside your stomach |
Carrie Arnold |
2013 |
Mental Disorders |
| Usefulness of HPHPA marker in a wide range of neurological, gastrointestinal, and psychiatric disorders |
Shaw, William Ph.D |
2010 |
Mental Disorders |
| The Role of Cholesterol in Autism |
Shaw, William Ph.D |
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Mental Disorders |
| The Unique Vulnerability of the Human Brain to Toxic Chemical Exposure and the Importance of Toxic Chemical Evaluation and Treatment in Orthomolecular Psychiatry |
Shaw, William Ph.D |
2010 |
Mental Disorders |
| The Tomato Effect |
Greenblatt, James M.D. |
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| The Implications of Low Cholesterol in Depression and Suicide |
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2014 |
Mental Disorders |
| National patterns in antidepressant medication treatment. |
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2009 |
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| Evaluation of outcomes with Citalopram for depression using measurement-based care in STAR*D: Implications for clinical practice. |
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2006 |
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| Clinical features of treatment-resistant depression. |
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2010 |
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| Influence of supplementary vitamins, minerals and essential fatty acids on the antisocial behaviour of young adult prisoners. |
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2002 |
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Gómez-Pinilla, F. Nature Reviews Neuroscience 9, 568-578 (July 2008) |
2008 |
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| Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.
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2007 |
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| Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome.
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2006 |
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| Fooling Mother Nature: Epigenetics and novel treatments for psychiatric Disorders
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| Omeprazole therapy causes malabsorption of cyanocobalamin (Vitamin B12)
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| Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from randomized, double-blind, placebo-controlled trial.
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2010 |
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| Rapid recovery from major depression using Magnesium treatment. |
Eby E, Eby K, Medical Hypotheses, 2006 |
2006 |
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| Is it time to trial vitamin D supplements for the prevention of schizophrenia? |
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2010 |
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| Low serum levels of 25-hydroxyvitamin D (25-OHD) among psychiatric out-patients in Sweden: relations with season, age, ethnic origin and psychiatric diagnosis. |
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2010 |
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| Tourette's syndrome: a cross sectional study to examine the PANDAS hypothesis. |
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2003 |
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2006 |
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| Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease. |
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2006 |
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| A case of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. |
Perlmutter, et al., Am J Psychiatry, 1998 |
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| Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumonia, and beta-hemolytic streptococci). |
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2003 |
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1995 |
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2000 |
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| Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of clostridia spp. In the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. |
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| Short-term benefit from oral vancomycin treatment of regressive-onset autism. |
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2000 |
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| Research suggests link between pesticides and brain disease. |
Gunderson D. Minnesota Public Radio, 2006 |
2006 |
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| Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease. |
Guillemin and Brew. Redox Rep, 2002 |
2002 |
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2007 |
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| Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia). |
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| The reaction of hyaluronic acid and its monomers, glucuronic acid and N-acetylglucosamine, with reactive oxygen species. |
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| Natural Products in the Clinical Treatment of Mental Illness: A Profile of Dr. James Greenblatt, M.D. |
Leonard, Joe |
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| ADHD |
Greenblatt, James M.D. |
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| Nutritional Supplements in ADHD |
Greeblatt, James M.D., Letter to the Editor of J Am Acad Child Adolesc Psychiatry, 38:10, October 1999 |
1999 |
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| Nutritional Treatment for Attention Deficit Hyperactivity Disorder: The Hype and the Hope - A Review of Current Research |
Greenblatt, James M.D. and Gina L. Nick, Ph.D., N.D. |
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Mental Disorders |
| Oligomeric Proanthocyanidins as an Alternative Treatment for ADHD: A Case Study |
Greenblatt, James M.D. |
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| Pycnogenol for ADHD? |
Steven W. Heimann, M.D., Letter to the Editor of J Am Acad Child Adolesc Psychiatry, 38:4, April 1999 |
1999 |
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| The Complete Assessment for Attention Deficit Hyperactivity Disorder |
Greenblatt, James M.D. |
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| Low Cholesterol and Its Psychological Effects |
Greenblatt, James M.D., The Breakthrough Depression Solution, June 10, 2011 |
2010 |
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| The Depressing News About Antidepressants (PDF) |
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| Rapid recovery from major depression using Magnesium treatment. |
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2001 |
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| A routine CBC leads to a non-routine diagnosis |
Middleman and Melchiono, Adolesc Med, 1996 |
1996 |
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| A case of mania secondary to vitamin B12 deficiency |
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1984 |
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| T-helper 1/T-helper 2 cytokine imbalance and clinical phenotypes of acute-phase major depression |
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2007 |
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Sutcigil, et al., Clin Dev Immunol, 2007 |
2007 |
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| The effects of tryptophan depletion on mood and psychiatric symptoms |
Van der Does, Journal of Affective Disorders, 2001 |
2001 |
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| Dietary tyrosine benefits cognitive and psychomotor performance during body cooling |
O'Brien, et al., Physiology & Behavior, 2007 |
2007 |
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| Enhancement of the antidepressant action of fluoxetine by folic acid: a randomized, placebo controlled trial |
Coppen and Bailey, Journal of Affective Disorders, 2000 |
2000 |
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| Folate, vitamin B12, and homocysteine in major depressive disorder |
Fava, et al., Am J Psychiatry, 1997 |
1997 |
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| Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression. |
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2004 |
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| Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity. |
Gilbody, et al. J Epidemiol Community Health, 2007 |
2007 |
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| Folic acid and the treatment of depression. |
Abou-Saleh & Copper, J Psychosom Res, 2006 |
2006 |
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| Folate and colorectal cancer: an evidence-based critical review. |
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2007 |
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| Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. |
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2005 |
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2009 |
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| S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. |
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2010 |
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| Zinc: the new antidepressant? |
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2006 |
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Nowak, Pol J Pharmacol, 2003 |
2003 |
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| Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study. |
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2009 |
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| Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's disease and Down syndrome. |
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2010 |
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| Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial. |
Stoll, et al., Arch Gen Psychiatry, 1999 |
1999 |
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| Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. |
Clayton, et al., Eur J Clin Nutr, 2009 |
2009 |
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2009 |
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| Successful treatment of bipolar disorder II and ADHD with micronutrient formula: a case study. |
Rucklidge and Harrison, CNS Spectr, 2010 |
2010 |
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| Effect of lithium maintenance on suicidal behavior in major mood disorders. |
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| Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation. |
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2010 |
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| Low serum cholesterol in suicide attempters. |
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1997 |
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| Association of low serum total cholesterol with major depression and suicide. |
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1999 |
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| Low serum cholesterol and external-cause mortality: potential implications for research and surveillance. |
Boscarino, et al., J Psychiatr Res, 2009 |
2009 |
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| Low serum HDL-cholesterol levels are associated with long symptom duration in patients with major depressive disorder. |
Lehto, et al., Psychiatry Clin Neurosci, 2010 |
2010 |
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| Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. |
Nemets, et al., Am J Psychiatry, 2006 |
2006 |
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| Omega-3 fatty acids in major depressive disorder: A preliminary double-blind, placebo-controlled trial. |
Su, et al., Eur Neuropsychoparmacol, 2003 |
2003 |
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| Effect of omega-3 fatty acids supplementation on depressive symptoms and on health-related quality of life in the treatment of elderly women with depression: a double-blind, placebo-controlled, randomized clinical trial. |
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2010 |
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| Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk. |
Sublette, et al., Am J Psychiatry, 2006 |
2006 |
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| Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents. |
Mamalakis, et al., Pharmacol Biochem Behav, 2006 |
2006 |
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| Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. |
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2009 |
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| Omega-3 fatty acid treatment of women with borderline personality disorder: a double-blind, placebo-controlled pilot study. |
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2003 |
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| Blood lead levels and major depressive disorder, panic disorder, and generalized anxiety disorder in US young adults. |
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2009 |
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| The role of catecholamines, 5-hydroxytryptamine and m-tyramine in the behavioural effects of m-tyrosine in the rat. |
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1982 |
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1995 |
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2007 |
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| Differential effects of cholesterol and 7-dehydrocholesterol on ligand binding of solubilized hippocampal serotonin1A receptors: implications in SLOS. |
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2007 |
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| Seasonal genetic influence on serum 25-hydroxyvitamin D levels: a twin study. |
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2003 |
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| Omega-3 fatty acids in major depressive disorder |
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| The efficacy of omega-3 supplementation for major depression: a randomized controlled trial |
Lesperance, et al., J Clin Psychiatry, 2010 |
2010 |
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| Beyond the Basics – New Approaches to Treatment of Anorexia Nervosa |
Greenblatt, James M.D., Chief Medical Officer, Walden Behavioral Care |
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| Clinical Treatment of Anorexia Nervosa Merits More Attention |
Greenblatt, James M.D., Chief Medical Officer, Walden Behavioral Care |
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| Excess mortality, causes of death and prognostic factors in anorexia nervosa. |
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2009 |
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2005 |
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2005 |
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| Fluoxetine after weight restoration in anorexia nervosa: a randomized controlled trial. |
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2006 |
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| Puberty moderates genetic influence on disordered eating. |
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2007 |
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1987 |
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| Oral zinc supplementation in anorexia nervosa. |
Safai-Kutti, Acta Psychiatr Scand Suppl, 1990 |
1990 |
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| Zinc status before and after zinc supplementation of eating disorder patients. |
McClain, et al., J Am Coll Nutr, 1992 |
1992 |
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| Zinc deficiency and childhood-onset anorexia nervosa. |
Lask, et al., J Clin Psychiatry, 1993 |
1993 |
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| Controlled trial of zinc supplementation in anorexia nervosa. |
Birmingham, et al., Int J Eat Disord. 1994 |
1994 |
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| Anorexia nervosa responding to zinc supplementation: a case report. |
Yamaguchi, et al., Gastroenterol Jpn, 1992 |
1992 |
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| A pilot open case series of ethyl-EPA supplementation in the treatment of anorexia nervosa. |
Ayton, et al., Prostaglandins Leukot Essent Fatty Acids, 2004 |
2004 |
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| Eating disorders: hope despite mortal risk. |
Kaye, W. Am J Psychiatry, 2009 |
2009 |
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| A peptide found in schizophrenia and autism causes behavioral changes in rats. |
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1999 |
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| Urinary peptide levels in women with eating disorders. A pilot study. |
Hellzen, et al., Eat Weight Disord, 2003 |
2003 |
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| Double-blind, controlled trial of Inositol treatment of depression. |
Levine, et al., Am J Psychiatry, 1995 |
1995 |
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| Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. |
Benjamin, et al., Am J Psychiatry, 1995 |
1995 |
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| Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. |
Palatnik, et al., J Clin Psychopharmacol, 2001 |
2001 |
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| Inositol treatment of obsessive-compulsive disorder. |
Fux, et al., Am J Psychiatry, 1996 |
1996 |
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| Effect of Inositol on bulimia nervosa and binge eating. |
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2001 |
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| Neurochemical individuality: genetic diversity among human dopamine and serotonin receptors and transporters. |
Cravchik A, Golman D. Arch Gen Psychiatry, 2000 |
2000 |
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| A randomized, double blind, placebo-controlled, prospective clinical study to demonstrate the clinical efficacy of a fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder. |
Koetter, et al., Phytother Res, 2007 |
2007 |
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| Can valerian improve the sleep of insomniacs after benzodiazepine withdrawal? |
Poyares, et al., Prog Neuropsychopharmacol Biol Psychiatry, 2002 |
2002 |
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| Niacinamide's potent role in alleviating anxiety with its benzodiazepine-like properties: a case report. |
Prousky, JE, Orthomol Med, 2004 |
2004 |
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| The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test. |
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1997 |
Sleep Disorders |
| Reasons to Perform Total IgG Food Allergy Testing Instead of IgG4 Food Allergy Testing. |
Shaw, William Ph.D |
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Food Allergies |
| New insight into the solution structures of wheat gluten proteins from Raman optical activity. |
Blanch, et al., Biochemistry, 2003 |
2003 |
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| Intestinal digestive resistance of immunodominant gliadin peptides. |
Hausch, et al., Am J Physiol Gastrointest Liver Physiol, 2002 |
2002 |
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| Advances in celiac disease and gluten-free diet. |
Niewinski NM, J AM Diet Assoc, 2008 |
2008 |
Food Allergies |
| Gluten sensitivity as a neurological illness. |
Hadjivassiliou, et al., J Neurol Neurosurg Psychiatry, 2002 |
2002 |
Food Allergies |
| Frontal cortical perfusion abnormalities related to gluten intake and associated autoimmune disease in adult celiac disease: 99m Tc-ECD brain SPECT study. |
Usai, et al., Dig Liver Dis, 2004 |
2004 |
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| Depression in adult untreated celiac subjects: diagnosis by the pediatrician. |
Corvaglia, et al., Am J Gastroenterol, 1999 |
1999 |
Food Allergies |
| Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs. |
Maes, et al., Acta Psychiatr Scand, 1996 |
1996 |
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| Lower activity of serum peptidases in abstinent alcohol-dependant patients. |
Maes, et al., Alcohol, 1999 |
1999 |
Food Allergies |
| Dipeptidyl peptidase IV and adenosine deaminase activity. Decrease in depression. |
Elgun, et al., Psychoneuroendocrinology, 1999 |
1999 |
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| Autism and Schizophrenia: Intestinal Disorders |
Cade, et al., Nutritional Neuroscience, 2000 |
2000 |
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| Beta-casomorphin induces fos-like immunoreactivity in discrete brain regions relevant to schizophrenia and autism. |
Sun, et al., Autism, 1999 |
1999 |
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| Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. |
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2002 |
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| Gliadin stimulates human monocytes to production of IL-8 and TNF-alpha through a mechanism involving NF-kappaB. |
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2004 |
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| Critical analysis of the diets of chronic juvenile offenders. |
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| Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults. |
Calderon-Garciduenas, et al., Toxicol Pathol, 2008 |
2008 |
Toxic Chemicals |
| An anthropological approach to the evaluation of preschool children exposed to pesticides in Mexico. |
Guillette, et al., Environ Health Perspect, 1998 |
1998 |
Toxic Chemicals |
| Medications as a source of human exposure to phthalates. |
Hauser, et al., Environ Health Perspect, 2004 |
2004 |
Toxic Chemicals |
| Origins of and Recognition of Micronutrient Deficiencies After Gastric Bypass Surgery |
Bal BS, et al., Curr Diab Rep., 2010 |
2010 |
Other |
| Dr. Greenblatt's Interview with Latitudes |
- |
- |
Other |
| Functional Psychiatry |
Greenblatt, James M.D. |
- |
Other |
| Ten Warning Signs of Good Health |
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- |
Other |
